Statins and All-Cause Mortality in High-Risk Primary Prevention
نویسندگان
چکیده
منابع مشابه
Statins are not associated with a decrease in all cause mortality in a high-risk primary prevention setting.
Low-density lipoprotein (LDL) cholesterol (LDL-C) is a risk factor for cardiovascular disease (CVD). Statins (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) lower LDL-C concentrations by about 30–50% and have been shown to reduce mortality in patients with prevalent CVD. However, it is not clear whether statin treatment is benefi cial in a primary prevention setting, that is in peo...
متن کاملCardiovascular risk prevention and all-cause mortality in primary care patients with an abdominal aortic aneurysm.
BACKGROUND Perioperative mortality is low for patients undergoing abdominal aortic aneurysm (AAA) repair, but long-term survival remains poor. Although patients diagnosed with AAA have a significant burden of cardiovascular disease and associated risk factors, there is limited understanding of the contribution of cardiovascular risk management to long-term survival. METHODS General practice r...
متن کاملStatins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 randomized controlled trials involving 65,229 participants.
BACKGROUND Statins have been shown to reduce the risk of all-cause mortality among individuals with clinical history of coronary heart disease. However, it remains uncertain whether statins have similar mortality benefit in a high-risk primary prevention setting. Notably, all systematic reviews to date included trials that in part incorporated participants with prior cardiovascular disease (CVD...
متن کاملHormone therapy and risk of all-cause mortality in women treated with statins.
Original Articles 369 Hormone therapy and risk of cardiovascular outcomes and mortality in women treated with statins Ingegärd Anveden Berglind, MD, PhD, Morten Andersen, MD, PhD, Anna Citarella, PhD, Marie Linder, PhD, Anders Sundström, PhD, and Helle Kieler, MD, PhD Hormone therapy was associated with reduced risks of all-cause mortality and no increased risks of cardiovascular disease in wom...
متن کاملReview: cholesterol-lowering treatment with statins reduces all-cause mortality in persons at risk.
M e t h o d s Data sources: {Computer databases, relevant journals, bibliographies of relevant articles, lists of conference abstracts, the trial register of the International Committee on Thrombosis and Haemostasis, researchers in the field, and manufacturers of lipid-modifying drugs}*. Study selection and assessment: Unconfounded randomized controlled trials (RCTs) that compared a statin with...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 2010
ISSN: 0003-9926
DOI: 10.1001/archinternmed.2010.182